Electrolytes and Arterial Muscle Contractility
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Electrolytes and Arterial Muscle Contractility
THAT changes in ionic gradients affect contractility and excitability has been shown in skeletal muscle,' cardiac muscle' ° and nerve." The reduction of external sodium causes reduction and eventual loss of excitability in nerve and skeletal muscle, supposedly because depolarization is due to the entry of sodium into the cell. The precise effect of alterations in external sodium on contractilit...
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The effect of specific electrolyte changes and of desoxycorticosterone on the responsiveness of vascular smooth muscle to epinephrine was studied using rabbit aortic strips. Low sodium increases, while high sodium decreases the epinephrine response. Conversely, low potassium decreases, while high potassium increases the epinephrine response. Desoxycorticosterone potentiates the epinephrine resp...
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1Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA 2Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA 3Department of Biomedical Sciences, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA 4Department of Neuroscience, Clinical Neurophysiology, Uppsala University, 751 ...
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FENN, WALLACE O.,TERENCE A. ROGERSANDELEONORE A. OHR. Muscle etectrdytes in acid and alkaline solutions. Am. J. Physiol. 194(2): 373-378. [email protected] frog muscles were equilibrated in solutions of varying pH and were then analyzed for potassium, sodium and sometimes chloride, phosphate, or bicarbonate. It was found that acid applied outside the muscle causes in most cases an increased loss of...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1960
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.8.2.451